• br OPG RANK and RANKL contribute to the

  2019-05-20

  

  OPG, RANK and RANKL contribute to the vicious cycle established between tumour erk pathway and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several arg

• Our group then carried out

  2019-05-18

  

  Our group then carried out a study to determine the substrate sites and arrhythmogenic mechanisms of the BrS [29]. We found that all our BrS patients had abnormal low voltage, fractionated late potentials exclusively clustering in the anterior aspect of the RVOT epicardium and not seen anywhere else

• Welcome to the new volume of the the official journal

  2019-05-18

  

  Welcome to the new volume of the , the official journal of the Japanese Heart Rhythm Society (JHRS) and the Asian Pacific Heart Rhythm Society (APHRS). The highlight of the 2013 volume is the publication of 2 . The first special issue is titled “Brugada syndrome from bench to bedside,” edited by gu

• As for the detection rate we should select

  2019-05-18

  

  As for the detection rate, we should select a different setting in patients with primary prevention and secondary prevention because ICD patients with primary prevention experience the faster lethal arrhythmia with an average rate of 200 beats per minute [27]. On the other hand, ICD recipients with

• MCL has a poor long term response

  2019-05-18

  

  MCL has a poor long-term response to current treatment strategies, for the most commonly used R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone), the remission rate is good (75–96%) but brief in duration. Despite the study of several other chemotherapy regimens

• Introduction Bone is a very

  2019-05-18

  

  Introduction Bone is a very dynamic tissue resulting from coordinated phases of formation and resorption called bone remodelling. Additional to its role in phosphocalcic homoeostasis, bone remodelling process is necessary for bone growth, for renewal of cellular and extracellular matrix components

• br Genetic basis for atrial standstill br Genetic basis of

  2019-05-18

  

  Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an

• br Results Compared to the respective untreated groups

  2019-05-18

  

  Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB

• br Discussion In our patient series

  2019-05-17

  

  Discussion In our patient series, coronary angiography was performed routinely prior to electrophysiological study, revealing a 9.1% (5/55) incidence of significant coronary artery stenosis in patients with Brugada syndrome/Brugada-type ECG. Although acute myocardial ischemia has been reported to

• p-Cresyl sulfate cost More recently Brugada et al used fleca

  2019-05-17

  

  More recently, Brugada et al. [131]. used flecainide to identify the full extent of low-voltage electrogram activity in the anterior RV and RVOT and targeted this region for RFA. In all 14 BrS patients, RFA eliminated abnormal bipolar electrograms, normalized ST-segment elevation on right precordial

• Studies using fixed site monitoring data rather than persona

  2019-05-17

  

  Studies using fixed-site monitoring data rather than personal monitoring data are subject to misclassification of the exposure because fixed site monitors do not account for individual mobility that affect exposure. Although, this typically results in non-differential exposure misclassification that

• Polysaccharides fatty acid esters glycosides iridoids

  2019-05-17

  

  Polysaccharides, fatty hbv virus esters, glycosides, iridoids, anthraquinones, flavonoids, phytosterols, carotenoids, vitamin A, antraquinones, potassium, and others have been identified as putative active ingredients in NJ. Our previous report indicated that gentisic, p-hydroxybenoic, and chloroge

• Successful and safe catheter ablation

  2019-05-17

  

  Successful and safe catheter ablation is facilitated by an appreciation for anatomical particularities and surgical details. Morphological analysis of clinically documented VT is also important. In these patients, VT usually shows a left bundle branch block-like QRS morphology and inferior frontal p

• Another problem is that the indications of each drug

  2019-05-17

  

  Another problem is that the indications of each drug differ among Asia-Pacific countries, and it protease inhibitor cocktail is difficult to provide recommendations that are consistent with the indications in each country. For example, in Japan, the 3 novel OACs are indicated for “the prevention of

• The principal difference between BrS and

  2019-05-17

  

  The principal difference between BrS and ERS is related to the region of the ventricle most affected. Epicardial mapping studies in BrS patients report accentuated J waves and fragmented and/or late potentials in the epicardial region of the RVOT [129–131], whereas in ERS only accentuated J waves, p

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