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To date over mutations in KCNQ have been found to
2019-05-08
To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [
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Zalcitabine manufacturer Lo and colleagues also add to the
2019-05-08
Lo and colleagues also add to the evidence that MDA might need to be widened beyond school-aged children (5–14 years). Different frequencies of treatment are known to be needed for communities with different intensities of infection, but less appreciated is that different age groups need to be treat
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In September a high level meeting of the UN
2019-05-08
In September 2011, a high-level meeting of the UN called for a concerted global response to the growing challenge of non-communicable diseases (NCDs). Subsequently, in 2013, the World Health Assembly adopted a WHO-generated action plan and set a target of 25 × 25: a 25% reduction in premature mortal
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Currently RFCA is indicated if pharmacologic therapies
2019-05-08
Currently, RFCA is indicated if pharmacologic therapies are unsuccessful [41]. Myocardial substrates for reentrant VT and/or the origin of focal VT are the ablation target for monomorphic VT storms. Although ablating multiple and unstable VTs is challenging, modern computerized mapping and catheter
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Studies and reports of lung
2019-05-08
Studies and reports of lung V5 Tag of GCTB are rare because of the low incidence of lung metastasis. The biological behavior and clinical features of GCTB are difficult to predict [6,7]. Some researchers have attempted to analyze related clinical factors of lung metastasis, such as age, sex, primar
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En este mismo orden de
2019-05-07
En este mismo orden de ideas, Brian McHale comenta que: Pons señala: Con esto, Pons reconoce que las novelas históricas contemporáneas de la región “no sólo plantean el problema de incluir en la reescritura de la historia lo excluido, lo silenciado, olvidado y reprimido por y en la historia, sino
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The distribution of dental treatments and
2019-05-07
The distribution of dental treatments and the number of treated teeth within each age group were also analyzed. The 6-years-old group had the lowest mean number of teeth treated by stainless-steel crown (SSC) and the lowest number undergoing pulp therapy (pGSK461364 and, when compared against 2015
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br Methods br Results In patients we analyzed
2019-05-07
Methods Results In 22 patients, we analyzed 82 sites at which HFS was delivered. We identified 57 GP-positive sites on the basis of a vagal response (19 at the MTGP, 18 at the SLGP, and 20 at the ARGP) and 25 GP-negative sites. After delivery of radiofrequency SCR 7 (30–35W for 30s) to the 57
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br Clinical characteristics Brugada syndrome is more common
2019-05-07
Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn
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Early recognition of ICD lead malfunction is desirable to
2019-05-07
Early recognition of ICD lead malfunction is desirable to prevent the life-threatening consequences of lead failure. Recent reports indicate that the majority of patients with ICD lead failure experience inappropriate ICD therapies, often as the presenting problem [4,6]. Regular device interrogation
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br Discussion In this case report
2019-05-07
Discussion In this case report, we demonstrated the consistent fusion of P-waves during CS os pacing, except for the last captured beat, which was entrained but not fused, thereby satisfying the entrainment criteria [2,3]. The tachycardia could be induced with reproducible results by a single atr
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The diagnostic infrastructure in the public sector
2019-05-07
The diagnostic infrastructure in the public sector relies mainly on sputum smear microscopy that cannot detect drug resistance. It is only when patients fail to get better on standard treatment, or have recurrence of tuberculosis, that they get screened for MDR-TB, resulting in morbidity, continued
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La construcci n de las dimensiones de la identidad
2019-05-07
La construcción de las dimensiones de la identidad es un proceso que se desarrolla en el marco de las relaciones sociales, tanto ctap través de los debates internos como en los contactos extragrupales. En este sentido la identidad se ve modelada, también, por las estructuras del poder existentes. Ro
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Agosto toma la medida del relato hist rico en
2019-05-07
Agosto toma la medida del relato histórico en algunas ocasiones, de la crónica periodística en otras, para obtener una narración que ha llegado a entremezclarse con la realidad, o al menos con una investigación académica bien documentada, al grado tal que es bastante común encontrarla citada en artí
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Predicting the potential effects of climate change
2019-05-07
Predicting the potential effects of climate change on the incidence and distribution of infectious gastroenteritis can assist public health providers to control and prevent severe outbreaks in the future. Implementation of programmes for rotavirus vaccination clearly shows benefit and should be an c
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