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Natural progestogens play an important role in the
2020-06-01
Natural progestogens play an important role in the stimulation of oocyte growth and maturation as well as in spermatogenesis and sperm maturation, and they act as sex pheromones in teleost fish (Kime, 1990, Kobayashi et al., 2002, Nagahama and Yamashita, 2008, Scott et al., 2010). A complex series o
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br The interaction network between the lncRNAs
2020-06-01
The interaction network between the lncRNAs which have been obtained from the previous steps, VDR and ESR was depicted using Cytoscape tool. Moreover, LncMAP tool (Li et al., 2018) was used to show transcriptional regulatory effects of two lncRNAs (MALAT1 and TBX5-AS1). The interaction network dep
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br Effects of estrogen on vascular function Atherosclerosis
2020-05-29
Effects of estrogen on vascular function Atherosclerosis is a chronic inflammatory condition of the vascular wall (Figure 1) that can be converted to an acute clinical event by the induction of plaque rupture or erosion, leading to thrombosis [58]. This perpetuating process is characterized by ph
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The Liver X Receptor and LXRs NR H
2020-05-29
The Liver X Receptor-α and -β (LXRs, NR1H3 and NR1H2, respectively) are members of the nuclear receptor superfamily that play a central role in controlling cholesterol homeostasis [9], [10]. In macrophages, LXRs can decrease the cellular sterol burden by inducing expression of the cholesterol efflux
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Similarly in the EAE model Chalmin et al previously demonstr
2020-05-29
Similarly in the EAE model, Chalmin et al. previously demonstrated that EBI2 and CH25H might be responsible for the efficient egress of differentiated Th17 cells from the draining lymph nodes [31]. As discussed above, in active EAE we did not find differences in EAE development and only the transfer
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br Localization of D receptors in striatum One characteristi
2020-05-29
Localization of D2 receptors in striatum One characteristic of D2Rs that has complicated their study is their expression in multiple neuronal populations within striatum, both pre- and postsynaptically (Beaulieu and Gainetdinov, 2011). In addition to spiny projection neurons (SPNs), which are the
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The methods for DNA MTase activity assay involve
2020-05-29
The methods for DNA MTase activity assay involve radioactive labelling [15], gel electrophoresis [16], high-performance liquid chromatography [17], [18], bisulfite conversion [19], [20], and affinity enrichment [21], [22]. In these methods, the methylated bases under the action of active MTase could
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Primidone mg Tamoxifen is included in the treatment protocol
2020-05-29
Tamoxifen is included in the treatment protocol of ER+ breast carcinoma patients routinely. Although tamoxifen improves patients\' survival, unfortunately a large number of ER+ patients don\'t response to tamoxifen treatment (Yager and Davidson, 2006). Detection of molecular markers which could take
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The first transcription factor TF known
2020-05-29
The first transcription factor (TF) known to interact with one of the cis-acting GAREs is GAMYB protein, the expression of which is induced by GA in the aleurone Gardiquimod of barley (HvGAMYB) (Gubler and Jacobsen, 1992). GAMYB is an important regulator of endosperm functions during seed developme
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Lisinopril dihydrate br Materials and methods br Results
2020-05-29
Materials and methods Results Discussion TP has aroused extensive explorations because of its potent anti-inflammatory, immune-suppressive and antitumor activities. Notwithstanding these, TP has yet to enter Phase II clinical trials owing to its severe toxicity (Zhou et al., 2012). TP could
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We and others have previously
2020-05-29
We and others have previously found that supplementation of old rats with ALCAR remediates the age-related decay in mitochondrial bioenergetics in liver (Hagen et al., 1998a, Hagen et al., 1998b), heart (Paradies et al., 1994, Paradies et al., 1999), muscle (Pesce et al., 2010) and H-Ser-OH (Liu et
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br Conclusions Enzyme can be delivered to
2020-05-29
Conclusions Enzyme can be delivered to the tumour by using humanised or fully human Schizandrin A or even loaded into synthetic nanospheres produced from silica [64] or liposomally entrapped [65]. For any future ADEPT developments, a number of basic points need to be considered. As immunogenicity
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3065 The data correlations from Multiflash and DIPPR were us
2020-05-29
The data correlations from Multiflash™ [43] and DIPPR [44] were used for the liquid volume and heat of vaporization. For vapour pressure the curves were regressed from the experimental data present on both the DIPPR [44] and TRC [45] databases. As for liquid heat capacities both the latter databases
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br Materials and methods br Results br Discussion Recently i
2020-05-29
Materials and methods Results Discussion Recently it has been found that prostaglandins play an important role in modulating the host immune system [1,3,22,23], and some parasites produce these eicosanoid mediators to survive into their hosts [6,[10], [11], [12],24,25]. The discovery that p
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In addition to through direct regulation of cell
2020-05-28
In addition to through direct regulation of cell differentiation, DDR2 may raise the abundance of myofibroblast subsets through advancing the recruitment of its precursor cells. One such evidence is that DDR2 can regulate lung fibroblast proliferation and migration. Another possibility rests on the
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